|
T16079 |
Mirodenafil
|
SK3530 |
PDE
|
|
Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction. |
|
TQ0126 |
Mirodenafil dihydrochloride
|
SK-3530 dihydrochloride |
PDE
|
|
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction. |
|
T14219 |
Aminaftone
|
Aminaphthone |
Endothelin Receptor
|
|
Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis. |
|
T1066L |
Ketanserin tartrate
|
KJK 945 tartrate,KJK-945 tartrate,KJK945 tartrate |
5-HT Receptor
,
Serotonin Transporter
,
Adrenergic Receptor
|
|
Ketanserin tartrate (KJK-945 tartrate) is a 5-HT2A receptor and α1-adrenergic receptor antagonist with antihypertensive activity, inhibits serotonin-induced vasoconstriction and platelet activation, and can be used in th... |
|
T11134 |
DZ2002
|
|
Others
|
|
DZ2002, an orally active, reversible, and low-cytotoxic type III SAHH inhibitor (Ki=17.9 nM), exhibits significant immunosuppressive activity. It effectively prevents experimental dermal fibrosis by reversing the profibr... |
|
T15560 |
Iloprost
|
ZK 36374,Ciloprost |
Others
|
|
Iloprost is a synthetic analogue of prostacyclin PGI2. Iloprost commonly employed in the treatment of peripheral vascular disease and also indicated in the treatment of patients affected by systemic sclerosis (SSc) in th... |
|
T62909 |
SGC agonist 2
|
|
|
|
SGC agonist 2 is a potent soluble guanylate cyclase (SGC) agonist. SGC agonist 2 has potential for cardiovascular disease (heart failure, angina, pulmonary hypertension, myocardial infarction) and fibrotic disease (renal... |
|
T63284 |
PAD-IN-2
|
|
|
|
PAD-IN-2 is a potent inhibitor of pad4 with an IC50 value <1 μM and can be used to study autoimmune diseases and cancers such as rheumatoid arthritis, vasculitis, systemic lupus erythematosus, cutaneous lupus erythematos... |
|
T62395 |
ALK5-IN-32
|
|
|
|
ALK5-IN-32 is a selective inhibitor of ALK-5 (10 nM<IC50<100 nM) and also inhibits TGF-β-induced SMAD signaling.ALK5-IN-31 has the potential to inhibit tumor growth in vivo.ALK5-IN-31 can be used in the study of prolifer... |
|
T62302 |
ALK5-IN-28
|
|
|
|
ALK5-IN-28 is a selective inhibitor of ALK-5 with an IC50 ≤ 10 nM that inhibits TGF-β-induced SMAD signalling.ALK5-IN-28 has the potential to inhibit tumour growth in vivo.ALK5-IN-28 can be used to study proliferative di... |
|
T62394 |
ALK5-IN-31
|
|
|
|
ALK5-IN-31 is a selective inhibitor of ALK-5 (IC50≤10 nM) and also inhibits TGF-β-induced SMAD signalling.ALK5-IN-31 has the potential to inhibit tumour growth in vivo.ALK5-IN-31 can be used in the study of proliferative... |
